Research Line
Integrated approach to the study of hematological diseases and the immune system /
Integrated approach to the study of hematological diseases and the immune system /
Medicine - Immunology and Allergology
Autonomic nervous system study
- Noninvasive systems of autonomic nervous system study applied to different diseases with participation in clinical trials.
- Evaluation of cardiovascular autonomic control for diagnosis and follow-up of patients with various diseases such as syncope and primary and secondary dysautonomias and for cardiovascular risk profiling in patients with chronic diseases.
- Application of non-invasive neuromodulation techniques of the autonomic nervous system for the treatment of dysautonomia, inflammation, and depressive symptoms in different cohorts of patients.
Systemic autoimmune diseases
- Development of predictive models for identifying patients at risk for complications related to the underlying disease.
- Single-center and multicenter clinical trials to identify risk factors, progression and response to therapy of systemic autoimmune diseases.
- Translational studies, particularly "Omics" analyses including gene expression, proteomics, microbiomics and metabolomics of systemic autoimmune diseases to identify risk factors, progression and response to therapy.
- Cellular models of immune-mediated diseases.
- Participation in national and international clinical trials
Syncope
- Risk stratification of patients with syncope in the emergency room
- Diagnostic yield of different methods for the study of patients with syncope
- Insight into the pathophysiological mechanisms related to syncope
Allergies
- Identification of new allergens and association between pollen allergy and Oral Allergy Syndrome, the main manifestation of food allergy in adults.
- Study of etiopathogenetic mechanisms and new therapies of chronic urticaria (the Center contributes to the drafting of Italian guidelines), allergic asthma, and drug allergy.
- Clinical, epidemiology and therapy of hymenoptera venom allergy (the Center contributes to the drafting of Italian guidelines and participates in international multicenter studies).
Other research programs
Clinical methodology: critical analysis of the scientific literature, diagnostic, prognostic and therapeutic meta-analysis and in-depth study of the tools used in the diagnostic pathway and to establish prognosis.
- Tilt Test Cot (Gardhen Scales)
- PowerLab system (ADInstruments) for ECG signal acquisition and respiratory activity
- Human NIBP Nano system (ADInstruments) for continuous blood pressure acquisition
- VITOS vagal stimulator (tVNS Technologies GmbH) for noninvasive auricular vagus nerve stimulation
- Pony FX spirometer (Cosmed)
- Airofit Pro (Airofit) for inspiratory muscle training
- European Space Agency (ESA) as part of the ESA Topical Team "Stress Challenges & Immunity in Space"
- Italian Space Agency (ASI) as part of the creation of the Roadmap for Space Life Sciences - Immunology
- Mayo Clinic, Rochester, Minnesota
- LMU Munich University Hospital, Munich, Germany
- University of California, Los Angeles
1 Full Professor, 1 Associate Professor, 1 Immunologist, 1 Allergist, 2 University Researcher, 1 Post Doctoral Researcher, 3 Research Assistant
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Other activities in this Research Line
Integrated approach to the study of hematological diseases and the immune system
Dermatology
Head
Angelo Valerio Marzano
Angelo Valerio Marzano
Hematology
Head
Francesco Passamonti
Francesco Passamonti
Infectious Diseases
Head
Alessandra Bandera
Alessandra Bandera
Medicine - Hemostasis and Thrombosis
Head
Flora Peyvandi
Flora Peyvandi
Medicine and Metabolic Disease
Head
Anna Ludovica Fracanzani
Anna Ludovica Fracanzani
Transfusion Medicine
Head
Daniele Prati
Daniele Prati
Neonatology and Neonatal Intensive Care Unit
Head
Monica Fumagalli
Monica Fumagalli
Clinical Pathology
Head
Matteo Vidali
Matteo Vidali
Pediatrics - Immunoreumatology
Head
Carlo Virginio Agostoni
Carlo Virginio Agostoni
Pediatrics - Pneumoinfectiology
Head
Carlo Virginio Agostoni
Carlo Virginio Agostoni